Modeling recapitulates the heterogeneous outcomes of SARS-CoV-2 infection and quantifies the differences in the innate immune and CD8 T-cell responses between patients experiencing mild and severe symptoms

SARS-CoV-2 infection results in highly heterogeneous outcomes, from cure without symptoms to acute respiratory distress and death. Empirical evidence points to the prominent roles of innate immune and CD8 T-cell responses in determining the outcomes. However, how these immune arms act in concert to...

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Detalles Bibliográficos
Autores principales: Chatterjee, Budhaditya, Singh Sandhu, Harshbir, Dixit, Narendra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269964/
https://www.ncbi.nlm.nih.gov/pubmed/35759522
http://dx.doi.org/10.1371/journal.ppat.1010630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269964/
https://www.ncbi.nlm.nih.gov/pubmed/35759522
http://dx.doi.org/10.1371/journal.ppat.1010630

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