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Cre/lox regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration

The ability to regulate gene activity spatially and temporally is essential to investigate cell-type-specific gene function during development and in postembryonic processes and disease models. The Cre/lox system has been widely used for performing cell and tissue-specific conditional analysis of ge...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Kambakam, Sekhar, Almeida, Maira P, Ming, Zhitao, Welker, Jordan M, Wierson, Wesley A, Schultz-Rogers, Laura E, Ekker, Stephen C, Clark, Karl J, Essner, Jeffrey J, McGrail, Maura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270027/
https://www.ncbi.nlm.nih.gov/pubmed/35713402
http://dx.doi.org/10.7554/eLife.71478