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Cre/lox regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration
The ability to regulate gene activity spatially and temporally is essential to investigate cell-type-specific gene function during development and in postembryonic processes and disease models. The Cre/lox system has been widely used for performing cell and tissue-specific conditional analysis of ge...
Autores principales: | Liu, Fang, Kambakam, Sekhar, Almeida, Maira P, Ming, Zhitao, Welker, Jordan M, Wierson, Wesley A, Schultz-Rogers, Laura E, Ekker, Stephen C, Clark, Karl J, Essner, Jeffrey J, McGrail, Maura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270027/ https://www.ncbi.nlm.nih.gov/pubmed/35713402 http://dx.doi.org/10.7554/eLife.71478 |
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