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Niche-specific genome degradation and convergent evolution shaping Staphylococcus aureus adaptation during severe infections

During severe infections, Staphylococcus aureus moves from its colonising sites to blood and tissues and is exposed to new selective pressures, thus, potentially driving adaptive evolution. Previous studies have shown the key role of the agr locus in S. aureus pathoadaptation; however, a more compre...

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Detalles Bibliográficos
Autores principales: Giulieri, Stefano G, Guérillot, Romain, Duchene, Sebastian, Hachani, Abderrahman, Daniel, Diane, Seemann, Torsten, Davis, Joshua S, Tong, Steven YC, Young, Bernadette C, Wilson, Daniel J, Stinear, Timothy P, Howden, Benjamin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270034/
https://www.ncbi.nlm.nih.gov/pubmed/35699423
http://dx.doi.org/10.7554/eLife.77195