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Structural and mechanistic insights into the inhibition of type I-F CRISPR-Cas system by anti-CRISPR protein AcrIF23

Prokaryotes evolved clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins as a kind of adaptive immune defense against mobile genetic elements including harmful phages. To counteract this defense, many mobile genetic elements in turn encode anti-CRIS...

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Detalles Bibliográficos
Autores principales: Ren, Junhui, Wang, Hao, Yang, Lingguang, Li, Feixue, Wu, Yao, Luo, Zhipu, Chen, Zeliang, Zhang, Yi, Feng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270243/
https://www.ncbi.nlm.nih.gov/pubmed/35697070
http://dx.doi.org/10.1016/j.jbc.2022.102124