A metal ion–dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase

The metal-dependent M17 aminopeptidases are conserved throughout all kingdoms of life. This large enzyme family is characterized by a conserved binuclear metal center and a distinctive homohexameric arrangement. Recently, we showed that hexamer formation in Plasmodium M17 aminopeptidases was control...

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Detalles Bibliográficos
Autores principales: Webb, Chaille T., Yang, Wei, Riley, Blake T., Hayes, Brooke K., Sivaraman, Komagal Kannan, Malcolm, Tess R., Harrop, Stephen, Atkinson, Sarah C., Kass, Itamar, Buckle, Ashley M., Drinkwater, Nyssa, McGowan, Sheena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270245/
https://www.ncbi.nlm.nih.gov/pubmed/35691342
http://dx.doi.org/10.1016/j.jbc.2022.102119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270245/
https://www.ncbi.nlm.nih.gov/pubmed/35691342
http://dx.doi.org/10.1016/j.jbc.2022.102119

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