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Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses

Plasmin is a broad-spectrum protease and therefore needs to be tightly regulated. Active plasmin is formed from plasminogen, which is found in high concentrations in the blood and is converted by the plasminogen activators. In the circulation, high levels of α2-antiplasmin rapidly and efficiently in...

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Detalles Bibliográficos
Autores principales: Loef, Evert J., Sheppard, Hilary M., Birch, Nigel P., Dunbar, P. Rod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270246/
https://www.ncbi.nlm.nih.gov/pubmed/35690148
http://dx.doi.org/10.1016/j.jbc.2022.102112