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Decorin knockdown is beneficial for aged tendons in the presence of biglycan expression

Decorin and biglycan are two major small leucine-rich proteoglycans (SLRPs) present in the tendon extracellular matrix that facilitate collagen fibrillogenesis, tissue turnover, and cell signal transduction. Previously, we demonstrated that knockout of decorin prevented the decline of tendon mechani...

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Detalles Bibliográficos
Autores principales: Beach, Zakary M., Dekhne, Mihir S., Rodriguez, Ashley B., Weiss, Stephanie N., Adams, Thomas H., Adams, Sheila M., Sun, Mei, Birk, David E., Soslowsky, Louis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270257/
https://www.ncbi.nlm.nih.gov/pubmed/35818471
http://dx.doi.org/10.1016/j.mbplus.2022.100114