Knockdown of sarcolipin (SLN) impairs substrate utilization in human skeletal muscle cells

BACKGROUND: Recent studies have highlighted that uncoupling of sarco-/endoplasmic reticulum Ca(2+)-ATPase (SERCA) by sarcolipin (SLN) increases ATP consumption and contributes to heat liberation. Exploiting this thermogenic mechanism in skeletal muscle may provide an attractive strategy to counterac...

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Detalles Bibliográficos
Autores principales: Mengeste, Abel M., Katare, Parmeshwar, Dalmao Fernandez, Andrea, Lund, Jenny, Bakke, Hege G., Baker, David, Bartesaghi, Stefano, Peng, Xiao-Rong, Rustan, Arild C., Thoresen, G. Hege, Kase, Eili Tranheim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270280/
https://www.ncbi.nlm.nih.gov/pubmed/35364719
http://dx.doi.org/10.1007/s11033-022-07387-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270280/
https://www.ncbi.nlm.nih.gov/pubmed/35364719
http://dx.doi.org/10.1007/s11033-022-07387-0

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