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Knockdown of sarcolipin (SLN) impairs substrate utilization in human skeletal muscle cells
BACKGROUND: Recent studies have highlighted that uncoupling of sarco-/endoplasmic reticulum Ca(2+)-ATPase (SERCA) by sarcolipin (SLN) increases ATP consumption and contributes to heat liberation. Exploiting this thermogenic mechanism in skeletal muscle may provide an attractive strategy to counterac...
Autores principales: | Mengeste, Abel M., Katare, Parmeshwar, Dalmao Fernandez, Andrea, Lund, Jenny, Bakke, Hege G., Baker, David, Bartesaghi, Stefano, Peng, Xiao-Rong, Rustan, Arild C., Thoresen, G. Hege, Kase, Eili Tranheim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270280/ https://www.ncbi.nlm.nih.gov/pubmed/35364719 http://dx.doi.org/10.1007/s11033-022-07387-0 |
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