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Pro-inflammatory cytokines mediate the epithelial-to-mesenchymal-like transition of pediatric posterior fossa ependymoma

Pediatric ependymoma is a devastating brain cancer marked by its relapsing pattern and lack of effective chemotherapies. This shortage of treatments is due to limited knowledge about ependymoma tumorigenic mechanisms. By means of single-nucleus chromatin accessibility and gene expression profiling o...

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Detalles Bibliográficos
Autores principales: Aubin, Rachael G., Troisi, Emma C., Montelongo, Javier, Alghalith, Adam N., Nasrallah, Maclean P., Santi, Mariarita, Camara, Pablo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270322/
https://www.ncbi.nlm.nih.gov/pubmed/35803925
http://dx.doi.org/10.1038/s41467-022-31683-9