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Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, and therapeutic options for advanced HCC are limited. Here, we observe that intestinal dysbiosis affects antitumor immune surveillance and drives liver disease progression towards cancer. Dysbiotic microbiota, as s...

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Detalles Bibliográficos
Autores principales: Schneider, Kai Markus, Mohs, Antje, Gui, Wenfang, Galvez, Eric J. C., Candels, Lena Susanna, Hoenicke, Lisa, Muthukumarasamy, Uthayakumar, Holland, Christian H., Elfers, Carsten, Kilic, Konrad, Schneider, Carolin Victoria, Schierwagen, Robert, Strnad, Pavel, Wirtz, Theresa H., Marschall, Hanns-Ulrich, Latz, Eicke, Lelouvier, Benjamin, Saez-Rodriguez, Julio, de Vos, Willem, Strowig, Till, Trebicka, Jonel, Trautwein, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270328/
https://www.ncbi.nlm.nih.gov/pubmed/35803930
http://dx.doi.org/10.1038/s41467-022-31312-5