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Recurrent somatic mutations as predictors of immunotherapy response

Immune checkpoint blockade (ICB) has transformed the treatment of metastatic cancer but is hindered by variable response rates. A key unmet need is the identification of biomarkers that predict treatment response. To address this, we analyzed six whole exome sequencing cohorts with matched disease o...

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Detalles Bibliográficos
Autores principales: Gajic, Zoran Z., Deshpande, Aditya, Legut, Mateusz, Imieliński, Marcin, Sanjana, Neville E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270330/
https://www.ncbi.nlm.nih.gov/pubmed/35803911
http://dx.doi.org/10.1038/s41467-022-31055-3