Cargando…
Recurrent somatic mutations as predictors of immunotherapy response
Immune checkpoint blockade (ICB) has transformed the treatment of metastatic cancer but is hindered by variable response rates. A key unmet need is the identification of biomarkers that predict treatment response. To address this, we analyzed six whole exome sequencing cohorts with matched disease o...
Autores principales: | Gajic, Zoran Z., Deshpande, Aditya, Legut, Mateusz, Imieliński, Marcin, Sanjana, Neville E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270330/ https://www.ncbi.nlm.nih.gov/pubmed/35803911 http://dx.doi.org/10.1038/s41467-022-31055-3 |
Ejemplares similares
-
Publisher Correction: Recurrent somatic mutations as predictors of immunotherapy response
por: Gajic, Zoran Z., et al.
Publicado: (2022) -
Massively parallel Cas13 screens reveal principles for guide RNA design
por: Wessels, Hans-Hermann, et al.
Publicado: (2020) -
The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy
por: Legut, Mateusz, et al.
Publicado: (2015) -
High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation
por: Legut, Mateusz, et al.
Publicado: (2020) -
Identification of combinations of somatic mutations that predict cancer survival and immunotherapy benefit
por: Gussow, Ayal B, et al.
Publicado: (2021)