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Melatonin ameliorates Parkinson’s disease via regulating microglia polarization in a RORα‐dependent pathway

An important pathophysiological component of Parkinson’s Disease (PD) is circadian rhythm disorder, closely related to a decrease in circulated melatonin (MLT) level. It has been reported recently that retinoic acid-associated orphan nuclear receptor (RORα), for the potentiallyendogenous ligand MLT,...

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Detalles Bibliográficos
Autores principales: Li, Jingwen, Liu, Hanshu, Wang, Xinyi, Xia, Yun, Huang, Jinsha, Wang, Tao, Lin, Zhicheng, Xiong, Nian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270337/
https://www.ncbi.nlm.nih.gov/pubmed/35803929
http://dx.doi.org/10.1038/s41531-022-00352-5