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Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states

Sodium-Potassium Pump (Na(+)/K(+)-ATPase, NKA) is an ion pump that generates an electrochemical gradient of sodium and potassium ions across the plasma membrane by hydrolyzing ATP. During each Post-Albers cycle, NKA exchanges three cytoplasmic sodium ions for two extracellular potassium ions through...

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Detalles Bibliográficos
Autores principales: Guo, Yingying, Zhang, Yuanyuan, Yan, Renhong, Huang, Bangdong, Ye, Fangfei, Wu, Liushu, Chi, Ximin, shi, Yi, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270386/
https://www.ncbi.nlm.nih.gov/pubmed/35803952
http://dx.doi.org/10.1038/s41467-022-31602-y