Cargando…

STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is associated with an incredibly dense stroma, which contributes to its recalcitrance to therapy. Cancer-associated fibroblasts (CAFs) are one of the most abundant cell types within the PDAC stroma and have context-dependent regulation of tumor progression in...

Descripción completa

Detalles Bibliográficos
Autores principales: Lefler, Julia E, MarElia-Bennett, Catherine B, Thies, Katie A, Hildreth, Blake E, Sharma, Sudarshana M, Pitarresi, Jason R, Han, Lu, Everett, Caroline, Koivisto, Christopher, Cuitino, Maria C, Timmers, Cynthia D, O’Quinn, Elizabeth, Parrish, Melodie, Romeo, Martin J, Linke, Amanda J, Hobbs, G Aaron, Leone, Gustavo, Guttridge, Denis C, Zimmers, Teresa A, Lesinski, Gregory B, Ostrowski, Michael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270499/
https://www.ncbi.nlm.nih.gov/pubmed/35803738
http://dx.doi.org/10.26508/lsa.202201460