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Monomeric C‐reactive protein induces the cellular pathology of Alzheimer's disease

INTRODUCTION: Human study shows that elevated C‐reactive protein (CRP) in blood impacts apolipoprotein E (APOE) ε4, but not APOE ε3 or APOE ε2, genotype to increase the risk of Alzheimer's disease (AD). However, whether CRP is directly involved in cellular AD pathogenesis and in which type of n...

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Detalles Bibliográficos
Autores principales: Gan, Qini, Wong, Alfred, Zhang, Zhengrong, Na, Hana, Tian, Hua, Tao, Qiushan, Rajab, Ibraheem M., Potempa, Lawrence A., Qiu, Wei Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270638/
https://www.ncbi.nlm.nih.gov/pubmed/35846159
http://dx.doi.org/10.1002/trc2.12319