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Modification of ginsenoside saponin composition via the CRISPR/Cas9-mediated knockout of protopanaxadiol 6-hydroxylase gene in Panax ginseng

BACKGROUND: The roots of Panax ginseng contain two types of tetracyclic triterpenoid saponins, namely, protopanaxadiol (PPD)-type saponins and protopanaxatiol (PPT)-type saponins. In P. ginseng, the protopanaxadiol 6-hydroxylase (PPT synthase) enzyme catalyses protopanaxatriol (PPT) production from...

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Detalles Bibliográficos
Autores principales: Choi, Han Suk, Koo, Hyo Bin, Jeon, Sung Won, Han, Jung Yeon, Kim, Joung Sug, Jun, Kyong Mi, Choi, Yong Eui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270645/
https://www.ncbi.nlm.nih.gov/pubmed/35818421
http://dx.doi.org/10.1016/j.jgr.2021.06.004