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Topical sirolimus solution for lingual microcystic lymphatic malformations in children and adults (TOPGUN): study protocol for a multicenter, randomized, assessor-blinded, controlled, stepped-wedge clinical trial

BACKGROUND: Lingual microcystic lymphatic malformations (LMLMs) are rare congenital vascular malformations presenting as clusters of cysts filled with lymph fluid or blood. Even small well-limited lesions can be responsible for a heavy burden, inducing pain, aesthetic prejudice, or oozing, bleeding,...

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Detalles Bibliográficos
Autores principales: Marchand, A., Caille, A., Gissot, V., Giraudeau, B., Lengelle, C., Bourgoin, H., Largeau, B., Leducq, S., Maruani, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270761/
https://www.ncbi.nlm.nih.gov/pubmed/35804404
http://dx.doi.org/10.1186/s13063-022-06365-y