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Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a diffuse parenchymal lung disease characterized by exuberant deposition of extracellular matrix (ECM) proteins in the lung interstitium, which contributes to substantial morbidity and mortality in IPF patients. Matrix metalloproteinases (MMPs) are...

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Detalles Bibliográficos
Autores principales: Bormann, Tina, Maus, Regina, Stolper, Jennifer, Tort Tarrés, Meritxell, Brandenberger, Christina, Wedekind, Dirk, Jonigk, Danny, Welte, Tobias, Gauldie, Jack, Kolb, Martin, Maus, Ulrich A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270768/
https://www.ncbi.nlm.nih.gov/pubmed/35804363
http://dx.doi.org/10.1186/s12931-022-02105-7