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An Integrative Transcriptomic Analysis Reveals EGFR Exon-19 E746-A750 Fragment Deletion Regulated miRNA, circRNA, mRNA and lncRNA Networks in Lung Carcinoma

INTRODUCTION: Competing endogenous RNA (ceRNA) appears to be an important post-transcriptional manner that regulates gene expression through a miRNA-mediated mechanism. Mutations in exon-19 of EGFR were frequently observed in lung cancer genes, which were associated with EGFR activity and EGFR-targe...

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Detalles Bibliográficos
Autores principales: Chen, Ling, Li, Shenyi, Shi, Weifeng, Wu, Yibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270948/
https://www.ncbi.nlm.nih.gov/pubmed/35818580
http://dx.doi.org/10.2147/IJGM.S370247