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The long non-coding RNA MEG8 induces an endothelial barrier through regulation of microRNA-370 and -494 processing

The 14q32 locus is an imprinted region in the human genome which contains multiple non-coding RNAs. We investigated the role of the long non-coding RNA maternally expressed gene 8 (MEG8) in endothelial function and its underlying mechanism. A 5-fold increase in MEG8 was observed with increased passa...

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Detalles Bibliográficos
Autores principales: Kremer, Veerle, Stanicek, Laura, van Ingen, Eva, Bink, Diewertje I., Hilderink, Sarah, Tijsen, Anke J., Wittig, Ilka, Mägdefessel, Lars, Nossent, Anne Yaël, Boon, Reinier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270956/
https://www.ncbi.nlm.nih.gov/pubmed/35611612
http://dx.doi.org/10.1242/jcs.259671