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Intranasal administration of cold-adapted live-attenuated SARS-CoV-2 candidate vaccine confers protection against SARS-CoV-2

With the COVID-19 pandemic globally, the ongoing threat of new challenges of mucosal infections was once again reminded human beings. Hence, access to the next-generation vaccine to elicit mucosal immunity is required to reduce virus shedding. SARS-CoV-2 retains a unique polybasic cleavage motif in...

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Detalles Bibliográficos
Autores principales: Abdoli, Mohsen, Shafaati, Maryam, Ghamsari, Ladan Kazem, Abdoli, Asghar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270963/
https://www.ncbi.nlm.nih.gov/pubmed/35820511
http://dx.doi.org/10.1016/j.virusres.2022.198857