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SyNPL: Synthetic Notch pluripotent cell lines to monitor and manipulate cell interactions in vitro and in vivo

Cell-cell interactions govern differentiation and cell competition in pluripotent cells during early development, but the investigation of such processes is hindered by a lack of efficient analysis tools. Here, we introduce SyNPL: clonal pluripotent stem cell lines that employ optimised Synthetic No...

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Detalles Bibliográficos
Autores principales: Malaguti, Mattias, Portero Migueles, Rosa, Annoh, Jennifer, Sadurska, Daina, Blin, Guillaume, Lowell, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270970/
https://www.ncbi.nlm.nih.gov/pubmed/35616331
http://dx.doi.org/10.1242/dev.200226