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Microarrayed human bone marrow organoids for modeling blood stem cell dynamics

In many leukemia patients, a poor prognosis is attributed either to the development of chemotherapy resistance by leukemic stem cells (LSCs) or to the inefficient engraftment of transplanted hematopoietic stem/progenitor cells (HSPCs) into the bone marrow (BM). Here, we build a 3D in vitro model sys...

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Detalles Bibliográficos
Autores principales: Giger, Sonja, Hofer, Moritz, Miljkovic-Licina, Marijana, Hoehnel, Sylke, Brandenberg, Nathalie, Guiet, Romain, Ehrbar, Martin, Kleiner, Esther, Gegenschatz-Schmid, Katharina, Matthes, Thomas, Lutolf, Matthias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270995/
https://www.ncbi.nlm.nih.gov/pubmed/35818479
http://dx.doi.org/10.1063/5.0092860