Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq

Understanding how breaks form and are repaired in the genome depends on the accurate measurement of the frequency and position of DNA double strand breaks (DSBs). This is crucial for identification of a chemical’s DNA damage potential and for safe development of therapies, including genome editing t...

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Detalles Bibliográficos
Autores principales: Dobbs, Felix M., van Eijk, Patrick, Fellows, Mick D., Loiacono, Luisa, Nitsch, Roberto, Reed, Simon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271039/
https://www.ncbi.nlm.nih.gov/pubmed/35810156
http://dx.doi.org/10.1038/s41467-022-31702-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271039/
https://www.ncbi.nlm.nih.gov/pubmed/35810156
http://dx.doi.org/10.1038/s41467-022-31702-9

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