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Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkers

Gene-environment interactions represent the modification of genetic effects by environmental exposures and are critical for understanding disease and informing personalized medicine. These often induce differential phenotypic variance across genotypes; these variance-quantitative trait loci can be p...

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Detalles Bibliográficos
Autores principales: Westerman, Kenneth E., Majarian, Timothy D., Giulianini, Franco, Jang, Dong-Keun, Miao, Jenkai, Florez, Jose C., Chen, Han, Chasman, Daniel I., Udler, Miriam S., Manning, Alisa K., Cole, Joanne B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271055/
https://www.ncbi.nlm.nih.gov/pubmed/35810165
http://dx.doi.org/10.1038/s41467-022-31625-5