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Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkers
Gene-environment interactions represent the modification of genetic effects by environmental exposures and are critical for understanding disease and informing personalized medicine. These often induce differential phenotypic variance across genotypes; these variance-quantitative trait loci can be p...
Autores principales: | Westerman, Kenneth E., Majarian, Timothy D., Giulianini, Franco, Jang, Dong-Keun, Miao, Jenkai, Florez, Jose C., Chen, Han, Chasman, Daniel I., Udler, Miriam S., Manning, Alisa K., Cole, Joanne B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271055/ https://www.ncbi.nlm.nih.gov/pubmed/35810165 http://dx.doi.org/10.1038/s41467-022-31625-5 |
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