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Different transcriptional responses by the CRISPRa system in distinct types of heterochromatin in Drosophila melanogaster

Transcription factors (TFs) activate gene expression by binding to elements close to promoters or enhancers. Some TFs can bind to heterochromatic regions to initiate gene activation, suggesting that if a TF is able to bind to any type of heterochromatin, it can activate transcription. To investigate...

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Detalles Bibliográficos
Autores principales: Ortega-Yáñez, Andrea, Cruz-Ruiz, Samantha, Vázquez, Martha, Zurita, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271074/
https://www.ncbi.nlm.nih.gov/pubmed/35810197
http://dx.doi.org/10.1038/s41598-022-15944-7