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Different transcriptional responses by the CRISPRa system in distinct types of heterochromatin in Drosophila melanogaster
Transcription factors (TFs) activate gene expression by binding to elements close to promoters or enhancers. Some TFs can bind to heterochromatic regions to initiate gene activation, suggesting that if a TF is able to bind to any type of heterochromatin, it can activate transcription. To investigate...
Autores principales: | Ortega-Yáñez, Andrea, Cruz-Ruiz, Samantha, Vázquez, Martha, Zurita, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271074/ https://www.ncbi.nlm.nih.gov/pubmed/35810197 http://dx.doi.org/10.1038/s41598-022-15944-7 |
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