Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA

Biomolecular condensation constitutes an emerging mechanism for transcriptional regulation. Recent studies suggest that the co-condensation between transcription factors (TFs) and DNA can generate mechanical forces driving genome rearrangements. However, the reported forces generated by protein-DNA...

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Detalles Bibliográficos
Autores principales: Nguyen, Tuan, Li, Sai, Chang, Jeremy T-H, Watters, John W., Ng, Htet, Osunsade, Adewola, David, Yael, Liu, Shixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271091/
https://www.ncbi.nlm.nih.gov/pubmed/35810158
http://dx.doi.org/10.1038/s41467-022-31738-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271091/
https://www.ncbi.nlm.nih.gov/pubmed/35810158
http://dx.doi.org/10.1038/s41467-022-31738-x

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