Acetyl-CoA-Carboxylase 1-mediated de novo fatty acid synthesis sustains Lgr5(+) intestinal stem cell function

Basic processes of the fatty acid metabolism have an important impact on the function of intestinal epithelial cells (IEC). However, while the role of cellular fatty acid oxidation is well appreciated, it is not clear how de novo fatty acid synthesis (FAS) influences the biology of IECs. We report h...

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Detalles Bibliográficos
Autores principales: Li, Shuting, Lu, Chia-Wen, Diem, Elia C., Li, Wang, Guderian, Melanie, Lindenberg, Marc, Kruse, Friederike, Buettner, Manuela, Floess, Stefan, Winny, Markus R., Geffers, Robert, Richnow, Hans-Hermann, Abraham, Wolf-Rainer, Grassl, Guntram A., Lochner, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271096/
https://www.ncbi.nlm.nih.gov/pubmed/35810180
http://dx.doi.org/10.1038/s41467-022-31725-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271096/
https://www.ncbi.nlm.nih.gov/pubmed/35810180
http://dx.doi.org/10.1038/s41467-022-31725-2

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