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Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression

OBJECTIVE: Intratumor heterogeneity drives cancer progression and therapy resistance. However, it has yet to be determined whether and how subpopulations of cancer cells interact and how this interaction affects the tumour. DESIGN: We have studied the spontaneous flow of extracellular vesicles (EVs)...

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Detalles Bibliográficos
Autores principales: Ruivo, Carolina F, Bastos, Nuno, Adem, Barbara, Batista, Ines, Duraes, Cecilia, Melo, Carlos A, Castaldo, Stephanie A, Campos‐Laborie, Francisco, Moutinho-Ribeiro, Pedro, Morão, Barbara, Costa-Pinto, Ana, Silva, Soraia, Osorio, Hugo, Ciordia, Sergio, Costa, Jose Luis, Goodrich, David, Cavadas, Bruno, Pereira, Luisa, Kouzarides, Tony, Macedo, Guilherme, Maio, Rui, Carneiro, Fatima, Cravo, Marília, Kalluri, Raghu, Machado, Jose Carlos, Melo, Sonia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
https://www.ncbi.nlm.nih.gov/pubmed/35012996
http://dx.doi.org/10.1136/gutjnl-2021-324994