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Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
OBJECTIVE: Intratumor heterogeneity drives cancer progression and therapy resistance. However, it has yet to be determined whether and how subpopulations of cancer cells interact and how this interaction affects the tumour. DESIGN: We have studied the spontaneous flow of extracellular vesicles (EVs)...
Autores principales: | Ruivo, Carolina F, Bastos, Nuno, Adem, Barbara, Batista, Ines, Duraes, Cecilia, Melo, Carlos A, Castaldo, Stephanie A, Campos‐Laborie, Francisco, Moutinho-Ribeiro, Pedro, Morão, Barbara, Costa-Pinto, Ana, Silva, Soraia, Osorio, Hugo, Ciordia, Sergio, Costa, Jose Luis, Goodrich, David, Cavadas, Bruno, Pereira, Luisa, Kouzarides, Tony, Macedo, Guilherme, Maio, Rui, Carneiro, Fatima, Cravo, Marília, Kalluri, Raghu, Machado, Jose Carlos, Melo, Sonia A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271144/ https://www.ncbi.nlm.nih.gov/pubmed/35012996 http://dx.doi.org/10.1136/gutjnl-2021-324994 |
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