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Structure of the human cation–chloride cotransport KCC1 in an outward-open state
Cation–chloride cotransporters (CCCs) catalyze electroneutral symport of Cl(−) with Na(+) and/or K(+) across membranes. CCCs are fundamental in cell volume homeostasis, transepithelia ion movement, maintenance of intracellular Cl(−) concentration, and neuronal excitability. Here, we present a cryoel...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271165/ https://www.ncbi.nlm.nih.gov/pubmed/35759661 http://dx.doi.org/10.1073/pnas.2109083119 |