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Structure of the human cation–chloride cotransport KCC1 in an outward-open state

Cation–chloride cotransporters (CCCs) catalyze electroneutral symport of Cl(−) with Na(+) and/or K(+) across membranes. CCCs are fundamental in cell volume homeostasis, transepithelia ion movement, maintenance of intracellular Cl(−) concentration, and neuronal excitability. Here, we present a cryoel...

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Detalles Bibliográficos
Autores principales:	Zhao, Yongxiang, Shen, Jiemin, Wang, Qinzhe, Ruiz Munevar, Manuel Jose, Vidossich, Pietro, De Vivo, Marco, Zhou, Ming, Cao, Erhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271165/ https://www.ncbi.nlm.nih.gov/pubmed/35759661 http://dx.doi.org/10.1073/pnas.2109083119

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