Noninvasive early detection of colorectal cancer by hypermethylation of the LINC00473 promoter in plasma cell-free DNA

BACKGROUND: Current noninvasive assays have limitations in the early detection of colorectal cancer. We evaluated the clinical utility of promoter methylation of the long noncoding RNA LINC00473 as a noninvasive biomarker to detect colorectal cancer and associated precancerous lesions. METHODS: We e...

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Detalles Bibliográficos
Autores principales: Ruiz-Bañobre, Juan, Rodriguez-Casanova, Aitor, Costa-Fraga, Nicolas, Bao-Caamano, Aida, Alvarez-Castro, Ana, Carreras-Presas, Martín, Brozos-Vazquez, Elena, Vidal-Insua, Yolanda, Vazquez-Rivera, Francisca, Candamio-Folgar, Sonia, Mosquera-Presedo, Manuel, Lago-Lestón, Ramón M., Muinelo-Romay, Laura, Vázquez-Bueno, José Ángel, Sanz-Pamplona, Rebeca, Moreno, Víctor, Goel, Ajay, Castillo, Lourdes, Martin, Ana C., Arroyo, Rocio, Esteller, Manel, Crujeiras, Ana B., López-López, Rafael, Díaz-Lagares, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271259/
https://www.ncbi.nlm.nih.gov/pubmed/35810318
http://dx.doi.org/10.1186/s13148-022-01302-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271259/
https://www.ncbi.nlm.nih.gov/pubmed/35810318
http://dx.doi.org/10.1186/s13148-022-01302-x

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