Cargando…

Noninvasive early detection of colorectal cancer by hypermethylation of the LINC00473 promoter in plasma cell-free DNA

BACKGROUND: Current noninvasive assays have limitations in the early detection of colorectal cancer. We evaluated the clinical utility of promoter methylation of the long noncoding RNA LINC00473 as a noninvasive biomarker to detect colorectal cancer and associated precancerous lesions. METHODS: We e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ruiz-Bañobre, Juan, Rodriguez-Casanova, Aitor, Costa-Fraga, Nicolas, Bao-Caamano, Aida, Alvarez-Castro, Ana, Carreras-Presas, Martín, Brozos-Vazquez, Elena, Vidal-Insua, Yolanda, Vazquez-Rivera, Francisca, Candamio-Folgar, Sonia, Mosquera-Presedo, Manuel, Lago-Lestón, Ramón M., Muinelo-Romay, Laura, Vázquez-Bueno, José Ángel, Sanz-Pamplona, Rebeca, Moreno, Víctor, Goel, Ajay, Castillo, Lourdes, Martin, Ana C., Arroyo, Rocio, Esteller, Manel, Crujeiras, Ana B., López-López, Rafael, Díaz-Lagares, Angel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271259/ https://www.ncbi.nlm.nih.gov/pubmed/35810318 http://dx.doi.org/10.1186/s13148-022-01302-x

Ejemplares similares

Evaluation of a Targeted Next-Generation Sequencing Panel for the Non-Invasive Detection of Variants in Circulating DNA of Colorectal Cancer
por: Rodríguez-Casanova, Aitor, et al.
Publicado: (2021)

Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study
por: Vidal Insua, Yolanda, et al.
Publicado: (2017)

Clinicopathological Profiles Associated with Discordant RAS Mutational Status between Liquid and Tissue Biopsies in a Real-World Cohort of Metastatic Colorectal Cancer
por: Brozos-Vázquez, Elena, et al.
Publicado: (2023)

Epigenetic Landscape of Liquid Biopsy in Colorectal Cancer
por: Rodriguez-Casanova, Aitor, et al.
Publicado: (2021)

Immunotherapy in patients with brain metastasis: advances and challenges for the treatment and the application of circulating biomarkers
por: Brozos-Vázquez, E. M., et al.
Publicado: (2023)

Clinical significance of baseline Pan-Immune-Inflammation Value and its dynamics in metastatic colorectal cancer patients under first-line chemotherapy
por: Pérez-Martelo, Martín, et al.
Publicado: (2022)

Publisher Correction: Epigenomic analysis reveals a unique DNA methylation program of metastasis-competent circulating tumor cells in colorectal cancer
por: Bao-Caamano, Aida, et al.
Publicado: (2023)

Epigenomic analysis reveals a unique DNA methylation program of metastasis-competent circulating tumor cells in colorectal cancer
por: Bao-Caamano, Aida, et al.
Publicado: (2023)

Evaluation of Circulating Tumor Cells and Related Events as Prognostic Factors and Surrogate Biomarkers in Advanced NSCLC Patients Receiving First-Line Systemic Treatment
por: Muinelo-Romay, Laura, et al.
Publicado: (2014)

Salivary DNA Methylation as an Epigenetic Biomarker for Head and Neck Cancer. Part I: A Diagnostic Accuracy Meta-Analysis
por: Rapado-González, Óscar, et al.
Publicado: (2021)

A genome-wide cell-free DNA methylation analysis identifies an episignature associated with metastatic luminal B breast cancer
por: Rodriguez-Casanova, Aitor, et al.
Publicado: (2022)

Clinical potential of circulating free DNA and circulating tumour cells in patients with metastatic non‐small‐cell lung cancer treated with pembrolizumab
por: Mondelo‐Macía, Patricia, et al.
Publicado: (2021)

Plasma cell-free DNA and circulating tumor cells as prognostic biomarkers in small cell lung cancer patients
por: Mondelo-Macía, Patricia, et al.
Publicado: (2022)

Somatic mutations in tumor and plasma of locoregional recurrent and/or metastatic head and neck cancer using a next‐generation sequencing panel: A preliminary study
por: Rapado‐González, Óscar, et al.
Publicado: (2022)

A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients
por: Pineda, Begoña, et al.
Publicado: (2019)

Integrity and quantity of salivary cell‐free DNA as a potential molecular biomarker in oral cancer: A preliminary study
por: Rapado‐González, Óscar, et al.
Publicado: (2022)

Plasma ctDNA RAS mutation analysis for the diagnosis and treatment monitoring of metastatic colorectal cancer patients
por: Vidal, J, et al.
Publicado: (2017)

Ascites-Derived Organoids to Depict Platinum Resistance in Gynaecological Serous Carcinomas
por: Arias-Diaz, Andrea Estrella, et al.
Publicado: (2023)

Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473
por: Tran, Khanh-Van, et al.
Publicado: (2020)

Do Clinical Trials Meet Current Care Needs? Views of Digestive Oncology Specialists in Galicia (Spain) Using the Delphi Method
por: Fernández Montes, Ana, et al.
Publicado: (2021)

EGFR-Based Immunoisolation as a Recovery Target for Low-EpCAM CTC Subpopulation
por: Vila, Ana, et al.
Publicado: (2016)

Effect of antiangiogenic-based treatment and systemic inflammatory factors on outcomes in patients with BRAF v600-mutated metastatic colorectal cancer: a real-world study in Spain
por: Martínez-Lago, Nieves, et al.
Publicado: (2021)

Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer
por: Palomeras, Sònia, et al.
Publicado: (2019)

Inhibition of α(1,6)fucosyltransferase: Effects on Cell Proliferation, Migration, and Adhesion in an SW480/SW620 Syngeneic Colorectal Cancer Model
por: López-Cortés, Rubén, et al.
Publicado: (2022)

Biosensors for the Detection of Circulating Tumour Cells
por: Costa, Clotilde, et al.
Publicado: (2014)

Weight of Different Intraocular Lenses: Evaluation of Toricity, Focality, Design, and Material
por: López-Vázquez, Ángel, et al.
Publicado: (2021)

LINC00473 as an Immediate Early Gene under the Control of the EGR1 Transcription Factor
por: Aliperti, Vincenza, et al.
Publicado: (2020)

Circulating microRNAs as Promising Biomarkers in Colorectal Cancer
por: Rapado-González, Óscar, et al.
Publicado: (2019)

ZNF577 Methylation Levels in Leukocytes From Women With Breast Cancer Is Modulated by Adiposity, Menopausal State, and the Mediterranean Diet
por: Lorenzo, Paula M., et al.
Publicado: (2020)

LINC00473 promotes the Taxol resistance via miR-15a in colorectal cancer
por: Wang, Lin, et al.
Publicado: (2018)

The clinical prognostic value of lncRNA LINC00473 in cancer patients: A meta-analysis
por: He, Yuanyang, et al.
Publicado: (2022)

Detection of MET Alterations Using Cell Free DNA and Circulating Tumor Cells from Cancer Patients
por: Mondelo-Macía, Patricia, et al.
Publicado: (2020)

Core Fucosylation Mediated by the FucT-8 Enzyme Affects TRAIL-Induced Apoptosis and Sensitivity to Chemotherapy in Human SW480 and SW620 Colorectal Cancer Cells
por: López-Cortés, Rubén, et al.
Publicado: (2023)

Clinical Application of Circulating Tumour Cells in Prostate Cancer: From Bench to Bedside and Back
por: León-Mateos, Luis, et al.
Publicado: (2016)

Molecular Characterization of Circulating Tumor Cells in Human Metastatic Colorectal Cancer
por: Barbazán, Jorge, et al.
Publicado: (2012)

DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling
por: Kim, Stephanie S., et al.
Publicado: (2022)

Expression of the primate-specific LINC00473 RNA in mouse neurons promotes excitability and CREB-regulated transcription
por: Pruunsild, Priit, et al.
Publicado: (2023)

Analysis of a Real-World Cohort of Metastatic Breast Cancer Patients Shows Circulating Tumor Cell Clusters (CTC-clusters) as Predictors of Patient Outcomes
por: Costa, Clotilde, et al.
Publicado: (2020)

Human salivary microRNAs in Cancer
por: Rapado-González, Óscar, et al.
Publicado: (2018)

A logistic model for the detection of circulating tumour cells in human metastatic colorectal cancer
por: Barbazán, Jorge, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6m893jcn71muoo53uutia1p1mt