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Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold

Rubella, a viral disease characterized by a red skin rash, is well controlled because of an effective vaccine, but outbreaks are still occurring in the absence of available antiviral treatments. The Rubella virus (RUBV) papain-like protease (RubPro) is crucial for RUBV replication, cleaving the nons...

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Detalles Bibliográficos
Autores principales: Cheong, Ezekiel Ze Ken, Quek, Jun Ping, Xin, Liu, Li, Chaoqiang, Chan, Jing Yi, Liew, Chong Wai, Mu, Yuguang, Zheng, Jie, Luo, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271420/
https://www.ncbi.nlm.nih.gov/pubmed/35835220
http://dx.doi.org/10.1016/j.jbc.2022.102250