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Dihydroartemisinin regulates immune cell heterogeneity by triggering a cascade reaction of CDK and MAPK phosphorylation

Artemisinin (ART) and dihydroartemisinin (DHA), apart from their profound anti-malaria effect, can also beneficially modulate the host immune system; however, the underlying molecular mechanisms remain unclear. Here, we report that DHA selectively induced T-cell activation, with an increased proport...

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Detalles Bibliográficos
Autores principales: Li, Qilong, Yuan, Quan, Jiang, Ning, Zhang, Yiwei, Su, Ziwei, Lv, Lei, Sang, Xiaoyu, Chen, Ran, Feng, Ying, Chen, Qijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271464/
https://www.ncbi.nlm.nih.gov/pubmed/35811310
http://dx.doi.org/10.1038/s41392-022-01028-5