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Dihydroartemisinin regulates immune cell heterogeneity by triggering a cascade reaction of CDK and MAPK phosphorylation
Artemisinin (ART) and dihydroartemisinin (DHA), apart from their profound anti-malaria effect, can also beneficially modulate the host immune system; however, the underlying molecular mechanisms remain unclear. Here, we report that DHA selectively induced T-cell activation, with an increased proport...
Autores principales: | Li, Qilong, Yuan, Quan, Jiang, Ning, Zhang, Yiwei, Su, Ziwei, Lv, Lei, Sang, Xiaoyu, Chen, Ran, Feng, Ying, Chen, Qijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271464/ https://www.ncbi.nlm.nih.gov/pubmed/35811310 http://dx.doi.org/10.1038/s41392-022-01028-5 |
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