Cargando…

Structural and functional analysis of the human cone‐rod homeobox transcription factor

The cone‐rod homeobox (CRX) protein is a critical K50 homeodomain transcription factor responsible for the differentiation and maintenance of photoreceptor neurons in the vertebrate retina. Mutant alleles in the human gene encoding CRX result in a variety of distinct blinding retinopathies, includin...

Descripción completa

Detalles Bibliográficos
Autores principales: Clanor, Penelope‐Marie B., Buchholz, Christine N., Hayes, Jonathan E., Friedman, Michael A., White, Andrew M., Enke, Ray A., Berndsen, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271546/
https://www.ncbi.nlm.nih.gov/pubmed/35255174
http://dx.doi.org/10.1002/prot.26332