Mechanisms Underlying C-type Inactivation in Kv Channels: Lessons From Structures of Human Kv1.3 and Fly Shaker-IR Channels

Voltage-gated potassium (Kv) channels modulate the function of electrically-excitable and non-excitable cells by using several types of “gates” to regulate ion flow through the channels. An important gating mechanism, C-type inactivation, limits ion flow by transitioning Kv channels into a non-condu...

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Detalles Bibliográficos
Autores principales: Ong, Seow Theng, Tyagi, Anu, Chandy, K. George, Bhushan, Shashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271579/
https://www.ncbi.nlm.nih.gov/pubmed/35833027
http://dx.doi.org/10.3389/fphar.2022.924289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271579/
https://www.ncbi.nlm.nih.gov/pubmed/35833027
http://dx.doi.org/10.3389/fphar.2022.924289

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