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Mechanisms Underlying C-type Inactivation in Kv Channels: Lessons From Structures of Human Kv1.3 and Fly Shaker-IR Channels
Voltage-gated potassium (Kv) channels modulate the function of electrically-excitable and non-excitable cells by using several types of “gates” to regulate ion flow through the channels. An important gating mechanism, C-type inactivation, limits ion flow by transitioning Kv channels into a non-condu...
Autores principales: | Ong, Seow Theng, Tyagi, Anu, Chandy, K. George, Bhushan, Shashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271579/ https://www.ncbi.nlm.nih.gov/pubmed/35833027 http://dx.doi.org/10.3389/fphar.2022.924289 |
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