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Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors

Coumarin and chalcone, two important kinds of natural product skeletons, both exhibit α-glucosidase inhibitory activity. In this work, coumarin-chalcone derivatives 3 (a∼v) were synthesized, and their α-glucosidase inhibitory activity was screened. The results showed that all synthetic derivatives (...

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Detalles Bibliográficos
Autores principales: Hu, Chun-Mei, Luo, Yong-Xin, Wang, Wen-Jing, Li, Jian-Ping, Li, Meng-Yue, Zhang, Yu-Fei, Xiao, Di, Lu, Li, Xiong, Zhuang, Feng, Na, Li, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271751/
https://www.ncbi.nlm.nih.gov/pubmed/35832461
http://dx.doi.org/10.3389/fchem.2022.926543