Minimizing Mitogenic Potency of Insulin Analogues Through Modification of a Disulfide Bond

The mechanisms by which insulin activates the insulin receptor to promote metabolic processes and cellular growth are still not clear. Significant advances have been gained from recent structural studies in understanding how insulin binds to its receptor. However, the way in which specific interacti...

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Detalles Bibliográficos
Autores principales: Ong, Shee Chee, Belgi, Alessia, Merriman, Allanah L., Delaine, Carlie A., van Lierop, Bianca, Andrikopoulos, Sofianos, Robinson, Andrea J., Forbes, Briony E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271792/
https://www.ncbi.nlm.nih.gov/pubmed/35832429
http://dx.doi.org/10.3389/fendo.2022.907864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271792/
https://www.ncbi.nlm.nih.gov/pubmed/35832429
http://dx.doi.org/10.3389/fendo.2022.907864

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