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Minimizing Mitogenic Potency of Insulin Analogues Through Modification of a Disulfide Bond
The mechanisms by which insulin activates the insulin receptor to promote metabolic processes and cellular growth are still not clear. Significant advances have been gained from recent structural studies in understanding how insulin binds to its receptor. However, the way in which specific interacti...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271792/ https://www.ncbi.nlm.nih.gov/pubmed/35832429 http://dx.doi.org/10.3389/fendo.2022.907864 |