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Integrative pharmacogenomics revealed three subtypes with different immune landscapes and specific therapeutic responses in lung adenocarcinoma

BACKGROUND: Pharmacogenomics is crucial for individualized drug therapy and plays an increasingly vital role in precision medicine decision-making. However, pharmacogenomics-based molecular subtypes and their potential clinical significance remain primarily unexplored in lung adenocarcinoma (LUAD)....

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Detalles Bibliográficos
Autores principales: Ge, Xiaoyong, Liu, Zaoqu, Weng, Siyuan, Xu, Hui, Zhang, Yuyuan, Liu, Long, Dang, Qin, Guo, Chunguang, Beatson, Richard, Deng, Jinhai, Han, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271977/
https://www.ncbi.nlm.nih.gov/pubmed/35832634
http://dx.doi.org/10.1016/j.csbj.2022.06.064