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Targeting non-structural proteins of Hepatitis C virus for predicting repurposed drugs using QSAR and machine learning approaches

Hepatitis C virus (HCV) infection causes viral hepatitis leading to hepatocellular carcinoma. Despite the clinical use of direct-acting antivirals (DAAs) still there is treatment failure in 5–10% cases. Therefore, it is crucial to develop new antivirals against HCV. In this endeavor, we developed th...

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Detalles Bibliográficos
Autores principales: Kamboj, Sakshi, Rajput, Akanksha, Rastogi, Amber, Thakur, Anamika, Kumar, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271984/
https://www.ncbi.nlm.nih.gov/pubmed/35832613
http://dx.doi.org/10.1016/j.csbj.2022.06.060